Creatine safety throughout the lifespan

Legislation restricting the sale of creatine-containing products to children and adolescents is not based on scientific evidence which strongly supports the importance of creatine in the diet and its safety as a supplement.

Creatine intake and cancer

The study identified a significant linear negative correlation between dietary creatine intake and cancer risk among U.S. adults, particularly in males and overweight individuals.

Creatine and sleep habits and disorders

Our findings show that people who meet the recommended creatine intake levels may have a lower risk of mild sleep problems. This could pave the way for future studies to explore and confirm how dietary creatine might help in sleep health.

Assessing dietary creatine intake

This paper delineates the challenges linked to estimating creatine intake from a typical diet, and explores opportunities to improve the assessment of population-wide creatine intake.

DRI for creatine in infants

This special article explores creatine requirements for infants aged 0 to 12 months, presents a summary of creatine content in human milk, and proposes reference intakes for creatine in this population.

Creatine and pregnancy outcomes

Although maternal plasma creatine concentrations were highly conserved, creatine metabolism appears to adjust throughout pregnancy. An ability to maintain creatine concentrations through diet and shifts in endogenous synthesis may impact fetal growth.

Dietary creatine and neurofilament light chain

Utilizing 2013–2014 NHANES data, the current study found a negative correlation between dietary creatine intake and serum levels of neurofilament light chain (NfL; a biomarker for neuronal damage) in 1912 individuals aged 20–75 years. The observed pattern, where increased dietary creatine intake was associated with reduced circulating NfL levels, suggests potential protective effects of creatine against neuronal injury.

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