Metabolite super-pathways affected by meat consumption were primarily amino acids, in particular creatine, trans-4-hydroxyproline and pyroglutamine. We report a novel association between reported red meat intake and trans-4-hydroxyproline, an amino acid that forms part of the collagen structure with elevated levels observed following gelatin consumption. We also identified a unique association between reported intakes of red meat and poultry and circulating creatine levels, of which red meat is the major source and vegetarians have lower blood levels.